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ABCD-N Advanced Biology Course in Development and Cell biology - Nucleus

Master in Life Science, ENS
BIO-PG-ABCD-S2 | ABCD-N Advanced Biology Course in Development and Cell biology - Nucleus
Year : M1/M2 and PhD
Where : Biology department, ENS
Duration : 11 sessions of 2h, every Wednesdays 5:15-7:15 pm, from March 13th to June 12th 2024
Hours : 22h approx.
Maximum class size : 25 students
This course is also open to external students. Contact

Coordination

Clara Richet-Bourbousse (ENS)
Héloïse Muller (Curie)
Anahi Molla Herman (CIRB Collège de France)
Terence Strick (ENS)

To register, please send an email to Bofei MA before March 4th, 2024.

Credits

3 ECTS

Keywords

Nucleus | genome | chromatin | epigenetic | 3D organization | transcription | DNA replication | DNA repair

Course Prerequisites

For each session, the speaker will provide a review to read beforehand, and do a brief introduction at the beginning with what is needed to understand his/her lecture. Hence no prerequisite is required as long as the student is motivated enough by the topic to read the bibliography provided by the speaker before the session.

Course objectives and description

The course aims to provide a comprehensive overview of the latest research on nuclear processes, including gene transcription, silencing, DNA replication and DNA repair, with a focus on chromatin and epigenetic-based regulations and spatial genome organization and their relevance for developmental and environmental responses in diverse eukaryotic organisms (mammals, insects, plants, paramecium, and yeast). The lectures will be given by top researchers in their field, who have shined by their innovative and/or interdisciplinary approaches, such as single cell, state-of-the-art imaging or genomic approaches.

The course will cover a range of themes, including DNA methylation, histone variants and modifications, non-coding RNA, transposable elements biology, meiosis, telomere biology, genome compartmentalization, single molecule analysis, developmental and environmental response.

Organization

There will be two speakers per session. They will give an introduction for non-specialists followed by a conference-level presentation. The talk will be followed by a discussion session including a brief student article presentation.

Assessment

Validation for M1/M2 (with grades) : Article presentation + presentation of the speaker/topic (Maximum 10-12 students, 2 article presentations per session)

Validation for ENS diploma / Doctoral school (without grades) : assiduity (presence to at least 80% of the sessions), article presentation + presentation of the speaker/topic (Maximum 10-12 students, 2 article presentations per session)

Possible to attend the course without validation in the limit of room availability

Course material

Slides and online presentations will be made available (with agreement of the speaker of each session)