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T104 - Physics & biology II

Biology Master, ENS
Year : 1 (M1)
Semester : 1 (S1)

Course code :


Course name :

Physics & biology II

Coordinator :

Laurent BOURDIEU - Pascal MARTIN



Keywords :

Physics, perception, biomechanics, optical microscopy

Prerequisites for the course :

Not to be afraid of equations and a minimum of physics.

Course objectives and description :

The first part of the course aims at providing some physical understanding of hearing. The second part is dedicated to the physical principles of optical microscopy and to its applications in neurosciences.

Assessment / evaluation :

Oral exam

Course material (hand-outs, online presentation available, …) :


Suggested readings in relationship with the module content (textbook chapters, reviews, articles) :

Accompanying reviews on hearing :
  Martin P (2014), Physical principles of hearing, in Physics and Biology : From Molecules to Life.. (JF Allemand and P Desbiolles), pp 127-147, World Scientific.
  Hudspeth AJ (2008) Making and effort to listen : Mechanical amplification in the ear, Neuron 59:530-545
  Martin P (2008) Active hair-bundle motility of the hair cells of vestibular and auditory organs. In : Active processes and otoacoustic emissions (Manley GA, Popper AN, Fay RR, eds), pp 93-144. New York : Springer
  Fettiplace R, kim K Kyunghee (2014), The physiology of mechanoelectrical transduction channels in hearing. J Physiol Rev 94:951-986
Accompanying review on microscopy :
  Advances in Light Microscopy for Neuroscience, Brian A.Wilt, Laurie D. Burns, Eric TattWei Ho,Kunal K. Ghosh, Eran A. Mukamel, and Mark J. Schnitzer .Annu. Rev. Neurosci. 2009. 32:435–506 « Optical Microscopy », Michael W. Davidson and Mortimer Abramowitz
  Nonlinear magic : multiphoton microscopy in the biosciences. Zipfel WR, Williams RM, Webb WW. Nat Biotechnol. 2003 21(11):1369-77.