S09 - Neuron physiology
2023-2024 planning:
Master in Life Science, ENS
Year : 1 (M1)
Semester : 1 (S1)
Course code :
BIO-M1-S09-S1
Course name :
Neuron physiology
Coordinators :
ECTS :
6
Keywords :
neuronal excitability, neurotransmitters, ion channels, receptors, electrophysiology, cell imaging
Prerequisites for the course :
Basics in molecular and cellular biology, in neurophysiology and electrical circuits.
Course objectives and description :
This course aims at providing the basic knowledge and technical tools to address in-depth study of the operation of the nervous system. The functioning of neurons will be addressed both at the molecular and cellular levels with particular emphasis on the electrical properties and excitability of the neuronal membrane that is central to brain function.
Assessment / evaluation :
Written examination (2 hrs) consisting of both general questions on cellular neurophysiology and data analysis and comment.
Course material (hand-outs, online presentation available, …) :
Powerpoint presentations
Suggested readings in relationship with the module content (textbook chapters, reviews, articles) :
– Ionic Channels of Excitable Membranes by Bertil Hille, 3rd edition, 2001, Sinauer Associates
– The Synapse edited by M. Sheng, B. Sabatini and T. Südhof, 2012, Cold Spring Harbor Press
– Principles of Neural Science by Kandel, Schwartz, Jessell, Siegelbaum & Hudspeth, 5th edition, 2012, McGraw Hill
– Neuroscience by Purves and coll., 5th edition, 2012, Sinauer Associates